PEDEvidence@pedevidence

SOURCE-LINKED STUDY SUMMARY

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation.

EClinicalMedicine ·

Review

Full paper summarizedQuality not appraised
What was studied
Evidence review of approved anti-obesity medicines and investigational drugs, updating prior work with Medline and Embase searches.
Who / model studied
The review included 46 randomized trials and 8 systematic reviews or meta-analyses of adults with obesity, plus ongoing adult pipeline trials.
Studied dose & schedule
Dose and schedule have not yet been extracted for this summary.
What the study found
Available medicines improved weight and metabolic measures with differing potency. At the review date, evidence did not show reduced hard cardiovascular outcomes, and long-term mortality data remained scarce.
Limitations & context
Searches covered selected date windows and the pipeline search was updated through June 4, 2022. This synthesis is not one comparative trial, and the authors emphasized scarce long-term outcome evidence.

Read summary source ↗ · Prepared 9/22/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: full paper. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1016/j.eclinm.2023.101882

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