SOURCE-LINKED STUDY SUMMARY
Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes.
Abstract summarizedQuality not appraised
- What was studied
- Five-year STAMPEDE randomized-trial follow-up comparing bariatric surgery plus intensive medical therapy with medical therapy alone for diabetes.
- Who / model studied
- 150 adults with type 2 diabetes and BMI 27–43 randomized; 134 completed follow-up.
- Studied dose & schedule
- Roux-en-Y gastric bypass or sleeve gastrectomy added to intensive medical therapy; comparator received medical therapy alone.
- What the study found
- Weight changed −23%, −19% and −5% with bypass, sleeve and medical therapy. HbA1c ≤6.0%, with/without medication, occurred in 29%, 23% and 5% of completers. Primary-outcome intention-to-treat comparisons were not significant (P=0.08 and 0.17). One late reoperation was reported.
- Limitations & context
- Abstract assessment; follow-up of the original trial, not independent replication. Attrition and analysis choice affect interpretation. This historical medical comparator does not establish superiority over modern incretin therapy.
Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1056/nejmoa1600869