PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men.

The Journal of physiology ·

Human

Abstract summarizedQuality not appraised
What was studied
This randomized study asked whether resveratrol enhances cardiovascular and fitness adaptations to high-intensity exercise training in older men.
Who / model studied
Twenty-seven healthy, physically inactive older men, averaging 65 years, were randomized to resveratrol or placebo.
Studied dose & schedule
Participants took 250 mg trans-resveratrol or placebo daily while completing eight weeks of high-intensity exercise training.
What the study found
The placebo group’s VO2max increase was 45% greater. Only placebo reduced mean arterial pressure, and resveratrol abolished favorable exercise effects on LDL, triglycerides and the total-cholesterol/HDL ratio.
Limitations & context
This eight-week study was small, male-only and limited to healthy inactive older adults; the abstract does not report adverse-event or adherence details.

Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary

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Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1113/jphysiol.2013.258061

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