PEDEvidence

SOURCE-LINKED STUDY SUMMARY

Dietary inorganic nitrate improves mitochondrial efficiency in humans.

Cell metabolism ·

Human

Abstract summarizedQuality not appraised
What was studied
A double-blind crossover experiment tested whether dietary inorganic nitrate changes skeletal-muscle mitochondrial efficiency and whole-body oxygen use.
Who / model studied
Healthy volunteers underwent the dietary intervention; the abstract source does not report the sample size.
Studied dose & schedule
Dose and schedule were not reported in the source used for this summary.
What the study found
Nitrate improved the mitochondrial P/O ratio, lowered resting leak-type respiration, and the efficiency change correlated with reduced oxygen cost during exercise.
Limitations & context
Abstract assessment. These are mechanistic mitochondrial and oxygen-cost findings, not a direct test of race results, competition performance, training adaptation, or long-term clinical outcomes.

Read summary source ↗ · Prepared 10/6/2026 · AI-assisted, source-based summary

Review record & corrections

Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.

No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.

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Research findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.

Original publication ↗ · DOI: 10.1016/j.cmet.2011.01.004

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