SOURCE-LINKED STUDY SUMMARY
Effects of an oral androgen on muscle and metabolism in older, community-dwelling men.
Abstract summarizedQuality not appraised
- What was studied
- A randomized trial assessed whether oxymetholone could improve lean body mass, muscle strength and body composition in older men.
- Who / model studied
- The study enrolled 31 men aged 65–80 years; the paper identifies them as community-dwelling.
- Studied dose & schedule
- Participants received placebo or oxymetholone at 50 mg or 100 mg daily for 12 weeks. The paper describes the androgen as oral.
- What the study found
- Lean mass increased by 3.3 kg with 50 mg and 4.2 kg with 100 mg, versus 0.0 kg with placebo. Upper-body strength improved and trunk fat declined. HDL cholesterol fell by 19 and 23 mg/dl with 50 and 100 mg, respectively; alanine aminotransferase rose by 72 U/l with 100 mg.
- Limitations & context
- Study limitations were not stated in the abstract. Methodological quality has not been appraised.
Read summary source ↗ · Prepared 9/24/2026 · AI-assisted, source-based summary
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1152/ajpendo.00363.2002