SOURCE-LINKED STUDY SUMMARY
Effects of an oral androgen on muscle and metabolism in older, community-dwelling men.
What was studied?
A randomized trial assessed whether oxymetholone could improve lean body mass, muscle strength and body composition in older men.
What changed?
Lean mass increased by 3.3 kg with 50 mg and 4.2 kg with 100 mg, versus 0.0 kg with placebo. Upper-body strength improved and trunk fat declined. HDL cholesterol fell by 19 and 23 mg/dl with 50 and 100 mg, respectively; alanine aminotransferase rose by 72 U/l with 100 mg.
Who was studied?
The study enrolled 31 men aged 65–80 years; the paper identifies them as community-dwelling.
Studied exposure
Participants received placebo or oxymetholone at 50 mg or 100 mg daily for 12 weeks. The paper describes the androgen as oral.
What remains uncertain?
Study limitations were not stated in the abstract. Methodological quality has not been appraised.
Review record & corrections
Summary prepared: . Source scope: abstract. This is an AI-assisted source summary, not an independent clinician sign-off.
No public field-by-field revision history is available for this card yet. The date above is the summary date, not proof that every field was updated then.
Inspect the source · Correction policyResearch findings apply to the population and conditions studied. This educational summary is not a treatment recommendation or a formal assessment of study quality.
Original publication ↗ · DOI: 10.1152/ajpendo.00363.2002