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Mod GRF 1-29

Findings, possible implications, and reported experiences.

About Mod GRF 1-29

PeptideGH axis
Primary research area
GH axis · secretagogue research
Regulatory status
Investigational
Evidence level
Early pharmacology
Primary mechanism
Modified GHRH-fragment analogue; stimulates GH-axis signaling
Reference profile available · Coverage varies by section

Also known as modified GRF 1-29 · CJC-1295 no DAC · CJC-1295 without DAC

Mod GRF 1-29 is a research name for a modified growth-hormone-releasing-hormone fragment. It is commonly distinguished from long-acting CJC-1295 with DAC; the two labels should not share pharmacokinetic values without a source. [1][2]

Start with the research

An outcome-specific synthesis has not been prepared for this compound. This is a coverage gap, not evidence that it has no effect.

Open studies and trial records
Uses & research

The intended research question is stimulation of the growth-hormone and IGF-1 axis through GHRH-receptor signaling. A source-verified human clinical indication or no-DAC pharmacokinetic study was not identified in this profile. [1]

Known half-life

No source-verified value in this profile yet. A treatment schedule or duration of an effect is not a drug half-life.

Half-life describes how quickly the measured drug concentration falls by half. It does not set a dosing interval.
Evidence & important limits

The human half-life reported for long-acting CJC-1295 cannot be transferred to Mod GRF 1-29 or a product labeled no DAC. Hormone release is not the same as demonstrated muscle, recovery or longevity benefit, and long-term safety remains unestablished. [1][2]

Safety & evidence boundaries

Source-specific information, not a personal safety clearance or monitoring plan.

The human half-life reported for long-acting CJC-1295 cannot be transferred to Mod GRF 1-29 or a product labeled no DAC. Hormone release is not the same as demonstrated muscle, recovery or longevity benefit, and long-term safety remains unestablished.

Explore safety questions by system

These are literature filters, not claims that this compound causes each effect. A keyword match is not a confirmed adverse reaction.

Interactions, rare harms, long-term effects and reversibility require separate evidence. Do not infer they are absent when the sources here do not address them.

Identity, names & formulations

Canonical compound: Mod GRF 1-29 · modgrf129

Searchable names: modified GRF 1-29, CJC-1295 no DAC, CJC-1295 without DAC

Names share a parent research page. Different esters, salts, routes and brands are not assumed to have the same half-life, indication or exposure.

Combination evidence stays attached to the studied combination. It is not automatically assigned to each ingredient.

Understand the evidence types

Read the model and design first, then the population, outcome and limitations. These categories describe evidence, not a best-compound ranking.

Randomized human trials
Compare assigned interventions. Randomization does not by itself establish low bias or relevance to every population.
Controlled human studies
Use a comparison group; allocation and confounding still matter.
Prospective human research
Follows participants forward. It may be observational or interventional, so this is not a separate quality grade.
Observational human research
Describes associations. Confounding can explain differences.
Case reports and series
Useful for unusual events and safety signals, not reliable rates or effect sizes.
Animal research
Can test biology and function in a living model. Human exposure, benefit and safety remain separate questions.
Cell and tissue research
Tests responses in a preparation, including human-derived cells. It is not a human participant trial.
Mechanistic and computational evidence
Helps explain or predict a pathway; predictions need experimental and clinical testing.
Anecdotal reports
Self-reported experiences can generate questions. Product identity, selection bias and other interventions may be uncontrolled.

Systematic reviews synthesize studies and depend on their quality. Preprint status and abstract versus full-paper reading are separate labels. Citation popularity measures attention, not reliability. A study summary is not a formal quality appraisal.

Sources for this profile

  1. 1. PubMed search · modified GRF 1-29 Scientific database search · no-DAC identity and study coverage
  2. 2. Teichman et al., CJC-1295 human studies (2006) Study abstract · long-acting DAC form only

Reference facts checked 2026-09-16. Source scope is listed above; this is not a formal quality appraisal. See each label for full prescribing information.

Browse all studies

Study model describes the source. Confidence depends on methods, replication, population and outcome.

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